Retatrutide: What You Need to Know
- Kayleigh Coddington-Bishop
- Sep 21, 2025
- 3 min read
Updated: Sep 22, 2025
Weight-loss medications are one of the most talked-about health topics right now, and one name making headlines is Retatrutide.
At Radiant Glow & Aesthetics, we want to make sure you have clear, reliable information before considering any weight-loss treatment. Our weight-management clinic is run by a qualified pharmacist prescriber, so you can feel confident that you’re getting safe, professional advice.

What is Retatrutide?
Retatrutide is an investigational weight-loss drug developed by Eli Lilly. It’s sometimes called a ‘triple agonist’ because it targets three receptors in the body:
GLP-1 – helps control appetite and blood sugar
GIP – supports insulin release and may enhance weight loss
Glucagon – helps boost metabolism and fat burning
By acting on all three, Retatrutide has shown stronger results in trials than single- or dual-target medications like Wegovy or Mounjaro.
How Retatrutide Compares
Medication | How it Works | Average Weight Loss (Clinical Trials) | UK Status |
Retatrutide | Triple agonist (GLP-1 + GIP + glucagon) | Up to 24.2% at 48 weeks | ❌ Not licensed yet |
Mounjaro | Dual agonist (GLP-1 + GIP) | ~20% at 72 weeks | ✅ Licensed |
Wegovy | GLP-1 agonist | ~15% at 68 weeks | ✅ Licensed |
Whilst these numbers are exciting, it’s important to remember that Retatrutide is still being studied, and we don’t yet know its long-term safety profile.
Availability in the UK
At the time of writing, Retatrutide is NOT licensed or approved by the MHRA in the UK (or by the FDA in the U.S.).
It is only available through clinical trials
It cannot be legally prescribed, purchased, or supplied by UK clinics
Any site or person selling ‘Retatrutide’ is not offering the real thing – and buying from them is unsafe.
Why Black-Market Products Are Dangerous
There’s been a surge in ‘Godzilla’ or ‘Triple G’ weight loss jabs being sold on TikTok, Facebook, and other online platforms.
These products are:
Unregulated – no guarantee of dose or purity
Potentially harmful – risk of contamination and unpredictable side effects
Illegal – possession or sale of unlicensed medicines in the UK can carry fines or even prison sentences
Myth-Busting: The Truth About Retatrutide
Myth: “I can buy real Retatrutide online in the UK.”
Truth: Any product sold online is counterfeit, mislabelled, or unsafe. Real Retatrutide is only available in clinical trials.
Myth: “If it’s trending on TikTok, it must be safe.”
Truth: Social media is not regulated – and many promoted products are illegal and untested.
Myth: “I don’t need a consultation for weight-loss medication.”
Truth: A consultation ensures the medication is suitable, safe, and prescribed at the right dose for you.
Safety & Side Effects
Even in clinical trials, some participants experienced side effects such as nausea, vomiting, diarrhoea, and fatigue – similar to other GLP-1-based medications. This is why professional supervision is essential for anyone starting weight-loss treatment.
Safe, Approved Weight-Management Options
At Radiant Glow’s Weight Management Clinic, we offer licensed, evidence-based medications that are available right now in the UK, including:
We will only ever recommend treatments that are proven, regulated, and safe.
Why Choose Radiant Glow Aesthetics
Our clinic is run by a qualified pharmacist prescriber who can:
Assess your full health history
Discuss your goals and concerns
Recommend the safest, most effective treatment plan
Give access to an exercise programme to aid your journey
Support you through your weight-loss journey with expert follow-up
Your safety and long-term health always come first.
The Bottom Line
Retatrutide is a very promising medication – but it’s not available yet and black-market products are dangerous and illegal.
At Radiant Glow Aesthetics, we stay up to date with the latest clinical trials and will keep our patients informed when new treatments become available safely and legally.
Book your consultation today to discuss safe, effective weight-management options and take the first step towards a healthier, more confident you.






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