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Retatrutide: What You Need to Know

Updated: Sep 22, 2025


Weight-loss medications are one of the most talked-about health topics right now, and one name making headlines is Retatrutide.


At Radiant Glow & Aesthetics, we want to make sure you have clear, reliable information before considering any weight-loss treatment. Our weight-management clinic is run by a qualified pharmacist prescriber, so you can feel confident that you’re getting safe, professional advice.



What is Retatrutide?


Retatrutide is an investigational weight-loss drug developed by Eli Lilly. It’s sometimes called a ‘triple agonist’ because it targets three receptors in the body:


  • GLP-1 – helps control appetite and blood sugar

  • GIP – supports insulin release and may enhance weight loss

  • Glucagon – helps boost metabolism and fat burning


By acting on all three, Retatrutide has shown stronger results in trials than single- or dual-target medications like Wegovy or Mounjaro.


How Retatrutide Compares

Medication

How it Works

Average Weight Loss (Clinical Trials)

UK Status

Retatrutide

Triple agonist (GLP-1 + GIP + glucagon)

Up to 24.2% at 48 weeks

❌ Not licensed yet

Mounjaro

Dual agonist (GLP-1 + GIP)

~20% at 72 weeks

✅ Licensed

Wegovy

GLP-1 agonist

~15% at 68 weeks

✅ Licensed

Whilst these numbers are exciting, it’s important to remember that Retatrutide is still being studied, and we don’t yet know its long-term safety profile.


Availability in the UK


At the time of writing, Retatrutide is NOT licensed or approved by the MHRA in the UK (or by the FDA in the U.S.).


  • It is only available through clinical trials

  • It cannot be legally prescribed, purchased, or supplied by UK clinics


Any site or person selling ‘Retatrutide’ is not offering the real thing – and buying from them is unsafe.


Why Black-Market Products Are Dangerous


There’s been a surge in ‘Godzilla’ or ‘Triple G’ weight loss jabs being sold on TikTok, Facebook, and other online platforms.


These products are:


  • Unregulated – no guarantee of dose or purity

  • Potentially harmful – risk of contamination and unpredictable side effects

  • Illegal – possession or sale of unlicensed medicines in the UK can carry fines or even prison sentences


Myth-Busting: The Truth About Retatrutide


Myth: “I can buy real Retatrutide online in the UK.”

Truth: Any product sold online is counterfeit, mislabelled, or unsafe. Real Retatrutide is only available in clinical trials.


Myth: “If it’s trending on TikTok, it must be safe.”

Truth: Social media is not regulated – and many promoted products are illegal and untested.


Myth: “I don’t need a consultation for weight-loss medication.”

Truth: A consultation ensures the medication is suitable, safe, and prescribed at the right dose for you.


Safety & Side Effects


Even in clinical trials, some participants experienced side effects such as nausea, vomiting, diarrhoea, and fatigue – similar to other GLP-1-based medications. This is why professional supervision is essential for anyone starting weight-loss treatment.


Safe, Approved Weight-Management Options


At Radiant Glow’s Weight Management Clinic, we offer licensed, evidence-based medications that are available right now in the UK, including:



We will only ever recommend treatments that are proven, regulated, and safe.



Our clinic is run by a qualified pharmacist prescriber who can:


  • Assess your full health history

  • Discuss your goals and concerns

  • Recommend the safest, most effective treatment plan

  • Give access to an exercise programme to aid your journey

  • Support you through your weight-loss journey with expert follow-up


Your safety and long-term health always come first.


The Bottom Line


Retatrutide is a very promising medication – but it’s not available yet and black-market products are dangerous and illegal.


At Radiant Glow Aesthetics, we stay up to date with the latest clinical trials and will keep our patients informed when new treatments become available safely and legally.


Book your consultation today to discuss safe, effective weight-management options and take the first step towards a healthier, more confident you.

 
 
 

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